Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | MGAM | O43451 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | SI | P14410 | 5/20 | 0.63 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070119 | 0.87 | HRH3 (0.59) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL27782823 | 0.84 | KDM4E (0.61) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL10163324 | 0.82 | KDM4E (0.68) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL28851907 | 0.81 | KDM4E (0.70) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL20704323 | 0.80 | TAAR1 (0.65) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13514087 | 0.79 | KDM4E (0.79) | KDM4EMGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL20703938 | 0.78 | TAAR1 (0.63) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10131103 | 0.78 | KDM4E (0.65) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL23918236 | 0.78 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL1143313 | 0.78 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102225918-B | One class 1,2,3-thiadiazole formoxyl ureide compound and its production and use | LIER CHEMICAL CO., LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |
| CN-102225918-A | 1,2,3-thiadiazole formyl urea compounds as well as preparation method and application thereof | LIER CHEMICAL CO LTD | 2011-10-26 | — | — | CN | disclosed |