Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | SI | P14410 | 6/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040565 | 0.84 | KDM4E (0.63) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL11338103 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL2833531 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL45441 | 0.78 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| Hydrochloric Acid SCHEMBL3691525 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL368725 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL603197 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL11324204 | 0.76 | HSD17B1 (0.76) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL11337791 | 0.76 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL3829254 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |
| CN-101696216-A | Method for preparing 1,3,4-thiadiazole-p-[3,2-alpha] pyridine derivative by one-pot method | UNIV NORTHWEST NORMAL | 2010-04-21 | — | — | CN | disclosed |