Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | MGAM | O43451 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | SI | P14410 | 5/20 | 0.66 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725821 | 0.83 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL28851907 | 0.83 | KDM4E (0.70) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL6538646 | 0.79 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL6902047 | 0.79 | ALDH1A1 (1.00) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL1143313 | 0.79 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL1143676 | 0.79 | KDM4E (1.00) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL11340093 | 0.79 | MGAM (1.00) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL474273 | 0.79 | KDM4E (0.66) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL45441 | 0.78 | KDM4E (0.67) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL28040565 | 0.78 | KDM4E (0.63) | KDM4EMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892622-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | Korea Research Institute of Chemical Technology (KR) | 2021-10-13 | — | — | EP | disclosed |