Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.32 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500196 | 0.83 | — | — | |
| SCHEMBL21604095 | 0.79 | KDM4E (0.58) | LMNATSHRKDM4ECYP3A4SREBF2 | |
| SCHEMBL28292606 | 0.79 | LMNA (0.41) | ASIC3LMNATSHRKDM4ECYP3A4 | |
| SCHEMBL23453426 | 0.76 | HRH1 (0.57) | ASIC3LMNAKDM4ESYKHRH1 | |
| SCHEMBL2643200 | 0.76 | — | — | |
| SCHEMBL31453329 | 0.75 | KCNH2 (0.38) | ASIC3LMNATSHRKDM4ECYP3A4 | |
| SCHEMBL27799978 | 0.75 | KDM4E (0.41) | ASIC3LMNATSHRKDM4ECYP3A4 | |
| SCHEMBL22658428 | 0.75 | ASIC3 (0.35) | ASIC3LMNATSHRKDM4ECYP3A4 | |
| SCHEMBL19999903 | 0.75 | ASIC3 (0.35) | ASIC3LMNATSHRKDM4ECYP3A4 | |
| SCHEMBL30808849 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085512-A | Enteric virus 71 (EV71)-resistant thiadiazolidine derivatives | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-11-25 | — | — | CN | disclosed |