Styrene

Styrene

SCHEMBL2804062

C=Cc1ccccc1.c1c[nH]c(-c2ncc[nH]2)n1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.57
MTOR P42345 1/20 0.57
ADK P55263 1/20 0.57
ALDH1A1 P00352 5/20 0.54
TSHR P16473 1/20 0.54
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CSNK1A1 P48729 1/20 0.40
TYRO3 Q06418 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
ADRA2A P08913 1/20 0.40
KDM4E B2RXH2 2/20 0.40
IDO1 P14902 1/20 0.40
TAAR1 Q96RJ0 3/20 0.39
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28008939 0.81 ALDH1A1 (0.57) NISCHMTORADKALDH1A1TSHR
SCHEMBL28436215 0.81 NISCH (0.58) NISCHMTORADKALDH1A1TSHR
SCHEMBL8542514 0.74 CSNK1A1 (0.49) NISCHMTORADKALDH1A1MEN1
Styrene SCHEMBL27689506 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2
Styrene SCHEMBL28366334 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2
Styrene SCHEMBL27670659 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2
Styrene SCHEMBL27689510 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2
Styrene SCHEMBL6745975 0.73 ALDH1A1 (0.88) ALDH1A1TSHRCYP1A2CYP2C9MAPT
Styrene SCHEMBL5344586 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2
Styrene SCHEMBL27635230 0.73 ALDH1A1 (0.88) ALDH1A1TSHRMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100047537-A1 METHOD OF PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed