SCHEMBL28040749

SCHEMBL28040749

O=COc1ccc(SSc2ccc(OC=O)cc2Sc2ccccc2)c(Sc2ccccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.35
ADORA2A P29274 1/20 0.35
PDE7B Q9NP56 1/20 0.35
MAPT P10636 5/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
NSD2 O96028 1/20 0.33
MAPK1 P28482 1/20 0.33
CBFB Q13951 1/20 0.32
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040750 0.88 PDE7A (0.33) PDE7AADORA2APDE7BMAPTMEN1
SCHEMBL6512960 0.78 CYP1A2 (0.42) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL194156 0.77 HPGD (0.42) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL28832540 0.75 MEN1 (0.47) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL6517248 0.75 ALDH1A1 (0.41) PDE7AADORA2APDE7BMAPTMEN1
SCHEMBL27941964 0.70 ALDH1A1 (0.43) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL29083009 0.70 CYP1A2 (0.45) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL27923345 0.70 TRIM24 (0.38) ALDH1A1HPGDMAPK1CBFB
SCHEMBL6516382 0.68 PDE7A (0.56) PDE7APDE7BMEN1KMT2AALDH1A1
SCHEMBL6516534 0.68 HTR1A (0.49) PDE7APDE7BMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103446725-B Golf 邓禄普体育用品株式会社 2016-08-10 CN disclosed
CN-103372285-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-04-20 CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446723-B Golf DUNLOP SPORTS CO., LTD. (JP) 2015-11-18 CN disclosed