Quinoline

Quinoline

SCHEMBL28040754

C#Cc1cccc2cc[nH]c12.c1ccc2ncccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
AHR P35869 2/20 0.40
AXL P30530 1/20 0.40
NUDT1 P36639 1/20 0.40
NR4A2 P43354 1/20 0.35
GRM5 P41594 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
KEAP1 Q14145 1/20 0.33
DOT1L Q8TEK3 1/20 0.33
TRPA1 O75762 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
ADK P55263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27950148 0.86 ALDH1A1 (0.49) ALDH1A1AHRAXLNUDT1NR4A2
SCHEMBL18000241 0.83 AHR (0.55) AHRGRM5KEAP1TRPA1CA1
Quinoline SCHEMBL27753517 0.81 AHR (0.66) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL27846294 0.78 ALDH1A1 (0.53) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL27719792 0.78 ALDH1A1 (0.53) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL28065888 0.78 ALDH1A1 (0.53) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL27719790 0.75 ALDH1A1 (0.50) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL28816675 0.75 ALDH1A1 (0.63) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL843861 0.75 ALDH1A1 (0.63) ALDH1A1AHRAXLNUDT1NR4A2
Quinoline SCHEMBL28073739 0.75 ALDH1A1 (0.63) ALDH1A1AHRAXLNUDT1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105176135-A Indolinylporphyrin near infrared dyes for dye-sensitized solar cells, and preparation method thereof UNIV SICHUAN 2015-12-23 CN claimed
CN-105176135-B One kind is used for indoline base porphyrin nir dye and its preparation of DSSC 四川大学 2017-11-28 CN disclosed
CN-105176135-A Indolinylporphyrin near infrared dyes for dye-sensitized solar cells, and preparation method thereof UNIV SICHUAN 2015-12-23 CN disclosed