Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.63 |
| ▸ | ITGAL | P20701 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | ADK | P55263 | 1/20 | 0.63 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28073739 | 1.00 | ALDH1A1 (0.63) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL28292512 | 1.00 | ALDH1A1 (0.63) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL28816675 | 1.00 | ALDH1A1 (0.63) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL27739225 | 0.98 | ALDH1A1 (0.61) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL27940258 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL27929380 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL28862645 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL27685453 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoline SCHEMBL27936663 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TRPA1CA1CA2ITGB2 | |
| Quinoxaline SCHEMBL5366555 | 0.89 | TRPA1 (0.68) | ALDH1A1TRPA1CA1CA2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116617226-B | Application of novel indole quinoline derivative as enterovirus 71 inhibitor | 湖北工业大学 | 2024-06-25 | — | — | CN | claimed |
| CN-116617226-A | Application of novel indole quinoline derivative as enterovirus 71 inhibitor | 湖北工业大学 | 2023-08-22 | — | — | CN | claimed |
| CN-113307804-B | Synthetic method and application of fluorine-containing indole quinoline compound | 天津师范大学 | 2022-06-24 | — | — | CN | claimed |
| CN-109503572-B | Method for synthesizing indole quinoline compounds | 上海交通大学 | 2021-10-08 | — | — | CN | claimed |
| CN-113307804-A | Synthetic method and application of fluorine-containing indole quinoline compound | 天津师范大学 | 2021-08-27 | — | — | CN | claimed |
| CN-110590822-B | Method for synthesizing borated (silanized) indole and tetrahydroquinoline by one-pot method | 吉林大学 | 2021-07-06 | — | — | CN | claimed |
| CN-109608456-B | Synthesis method of quinoline derivative | 苏州大学 | 2020-05-29 | — | — | CN | claimed |
| CN-109180648-B | 7-alkyl-N-pyrimidine indoline compound and synthetic method thereof | 郑州大学 | 2020-01-17 | — | — | CN | claimed |
| CN-110526866-A | A kind of synthetic method of 2- quinolinones compound | UNIV SHANGHAI JIAOTONG | 2019-12-03 | — | — | CN | claimed |
| CN-105849096-B | Piperidine derivatives having multimodal activity against pain | 埃斯蒂文制药股份有限公司 | 2019-11-29 | — | — | CN | claimed |
| CN-101417971-B | Indolines compounds, preparation method and pharmaceutical application thereof | UNIV CHINA PHARMA | 2011-04-20 | — | — | CN | claimed |
| CN-1757083-B | Chip type solid electrolytic capacitor | SHOWA DENKO KK | 2010-06-09 | — | — | CN | claimed |
| CN-1748271-B | Capacitor and production method of the capacitor | SHOWA DENKO KK | 2010-06-02 | — | — | CN | claimed |
| CN-101560178-A | Polysubstituted indoline compound, preparation method and medical application thereof | UNIV CHINA PHARMA (CN) | 2009-10-21 | — | — | CN | claimed |
| CN-101417971-A | Indolines compounds, preparation method and pharmaceutical application thereof | UNIV CHINA PHARMA (CN) | 2009-04-29 | — | — | CN | claimed |
| CN-1984893-A | Method for producing onium salts with a low chloride content | MERCK PATENT GMBH (DE) | 2007-06-20 | — | — | CN | claimed |
| CN-1757083-A | Chip type solid electrolytic capacitor | SHOWA DENKO KK (JP) | 2006-04-05 | — | — | CN | claimed |
| CN-1748271-A | Capacitor and production method of the capacitor | SHOWA DENKO KK (JP) | 2006-03-15 | — | — | CN | claimed |
| CN-1235882-C | Aliphatic amino substituted indole quinoline derivatives, their preparation method and pharmaceutical application | UNIV SUN YAT SEN (CN) | 2006-01-11 | — | — | CN | claimed |
| CN-1546473-A | Aliphatic amino substituted indole quinoline derivatives, their preparation method and pharmaceutical application | 中山大学 | 2004-11-17 | — | — | CN | claimed |