Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887424 | 0.79 | TAAR1 (0.39) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12815012 | 0.79 | LMNA (0.34) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27905433 | 0.79 | L3MBTL1 (0.37) | TAAR1HTR2A | |
| SCHEMBL1548462 | 0.78 | TAAR1 (0.33) | TAAR1MAOAHTR2AHRH1 | |
| SCHEMBL15915020 | 0.76 | LMNA (0.38) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15914960 | 0.76 | LMNA (0.38) | TAAR1MAOASIGMAR1LMNATRPA1 | |
| SCHEMBL10454800 | 0.72 | TSHR (0.38) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2269772 | 0.72 | LMNA (0.35) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8344995 | 0.71 | TP53 (0.35) | TAAR1MAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27669962 | 0.71 | TAAR1 (0.38) | TAAR1MAOASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |