SCHEMBL28040892

SCHEMBL28040892

O=POc1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
HSD17B10 Q99714 4/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 8/20 0.36
HPGD P15428 4/20 0.36
KDM4E B2RXH2 3/20 0.36
CFD P00746 2/20 0.36
GAA P10253 2/20 0.34
TP53 P04637 1/20 0.33
USP2 O75604 1/20 0.33
PDE3A Q14432 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MYC P01106 1/20 0.33
AKR1C4 P17516 2/20 0.32
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
AKR1C1 Q04828 2/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831084 0.89 ESR1 (0.37) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL28091450 0.76 CA12 (0.47) TSHRALDH1A1KDM4ECFDGAA
SCHEMBL28040875 0.76 CA12 (0.47) TSHRALDH1A1KDM4EGAATP53
SCHEMBL5009696 0.72 KDM4E (0.58) HSD17B10TSHRALDH1A1HPGDKDM4E
Pyromellitic Acid SCHEMBL22127 0.72 ALDH1A1 (0.53) HSD17B10TSHRALDH1A1HPGDKDM4E
Pyromellitic Acid SCHEMBL22443 0.72 ALDH1A1 (0.53) HSD17B10TSHRALDH1A1HPGDKDM4E
SCHEMBL5026767 0.70 LCK (0.42) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL14944744 0.70 LCK (0.42) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL5009702 0.69 CYP1A2 (0.38) HSD17B10TSHRALDH1A1HPGDKDM4E
Pyromellitic Acid SCHEMBL9485109 0.69 ALDH1A1 (0.50) HSD17B10TSHRALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995096-B Multi-layer bottle and manufacture method thereof 三菱瓦斯化学株式会社 2016-09-28 CN disclosed
CN-104995096-A Multi-layer bottle and method for producing same MITSUBISHI GAS CHEMICAL CO 2015-10-21 CN disclosed