SCHEMBL14944744

SCHEMBL14944744

O=COc1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
HSD17B10 Q99714 4/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 6/20 0.36
HPGD P15428 4/20 0.36
KDM4E B2RXH2 4/20 0.36
CFD P00746 2/20 0.36
GAA P10253 2/20 0.34
MAPT P10636 1/20 0.33
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MYC P01106 1/20 0.33
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP1A2 P05177 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001431 0.91 LCK (0.41) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL14904503 0.88 TSHR (0.42) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL12285464 0.81 ALOX5 (0.39) LCKFYNALDH1A1HPGDKDM4E
SCHEMBL16351578 0.81 ALDH1A1 (0.43) LCKFYNHSD17B10ALDH1A1HPGD
SCHEMBL12285929 0.80 ALDH1A1 (0.41) LCKFYNALDH1A1HPGDKDM4E
SCHEMBL13451132 0.80 LMNA (0.44) HSD17B10TSHRKDM4EGAAMAPT
SCHEMBL12349988 0.78 LCK (0.39) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL15425834 0.77 CFD (0.53) LCKHSD17B10ALDH1A1KDM4ECFD
SCHEMBL12285465 0.77 PRSS1 (0.33) LCKFYNHSD17B10TSHRKDM4E
SCHEMBL10027391 0.76 APP (0.37) LCKFYNHSD17B10TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11860538-B2 Photosensitive resin composition, heterocyclic ring-containing polymer precursor, cured film, laminate, method for producing cured film, and semiconductor device FUJIFILM CORPORATION (JP) 2024-01-02 US disclosed
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof ZHEJIANG UNIVERSITY (CN) 2023-10-10 US disclosed
US-20180222164-A1 LAMINATE, METHOD FOR MANUFACTURING LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 US disclosed
US-20180215874-A1 RESIN, COMPOSITION, CURED FILM, METHOD FOR MANUFACTURING CURED FILM AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-02 US disclosed
US-20180118887-A1 PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PRECURSOR COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-20180079864-A1 POLYIMIDE PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, A SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING POLYIMIDE PRECURSOR COMPOSITION FUJIFILM CORPORATION (JP) 2018-03-22 US disclosed
US-20170101521-A1 THERMAL BASE GENERATOR, THERMOSETTING RESIN COMPOSITION, CURED FILM, CURED FILM MANUFACTURING METHOD, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2017-04-13 US disclosed
US-9371403-B2 Hydrogenation of diene-based polymers LANXESS DEUTSCHLAND GMBH (DE) 2016-06-21 US disclosed
US-9217109-B2 Polymer-stabilised liquid-crystal media and displays MERCK PATENT GMBH (DE) 2015-12-22 US disclosed
US-20130119311-A1 POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof DUOX1, SOD1, DUOX2 LCK 762/4885FYN 1223/4885HSD17B10 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.