Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306284 | 0.82 | MMP2 (0.38) | ERCC5FEN1HDAC6 | |
| SCHEMBL13680965 | 0.80 | ERCC5 (0.55) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL31595961 | 0.76 | ERCC5 (0.58) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL28003535 | 0.75 | HDAC6 (0.46) | QPCTHDAC6 | |
| SCHEMBL2227416 | 0.74 | LOXL2 (0.64) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL28815683 | 0.74 | LOXL2 (0.55) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL28602757 | 0.73 | — | — | |
| SCHEMBL4873585 | 0.72 | LOXL2 (0.53) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL5677058 | 0.72 | LOXL2 (0.49) | ERCC5FEN1LOXL2LOXL3QPCT | |
| SCHEMBL25523340 | 0.71 | LOXL2 (0.51) | ERCC5FEN1LOXL2LOXL3QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |