Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 3/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442052 | 0.90 | PPARA (0.71) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL27897229 | 0.90 | PPARA (0.71) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL7405992 | 0.90 | PPARA (0.71) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL6806283 | 0.88 | ITGB3 (0.49) | PPARAPPARGHDAC4HDAC1HDAC6 | |
| SCHEMBL8615711 | 0.86 | PPARA (0.69) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL18261693 | 0.85 | ITGB3 (0.54) | PPARAPPARGKLK7KLK5ITGB3 | |
| SCHEMBL4846559 | 0.85 | ITGB3 (0.54) | PPARAPPARGKLK7KLK5ITGB3 | |
| SCHEMBL11374461 | 0.84 | ACE (0.62) | PPARAPPARGCTSSCTSKITGB3 | |
| SCHEMBL11512962 | 0.84 | ACE (0.62) | PPARAPPARGCTSSCTSKITGB3 | |
| SCHEMBL4750337 | 0.84 | ITGB3 (0.58) | KLK7KLK5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770435-B | Pyrazolopyrimidines and the purposes as PDE10 inhibitor thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |