Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17692 | 0.96 | — | — | |
| SCHEMBL15082542 | 0.96 | — | — | |
| SCHEMBL29850839 | 0.96 | ALDH1A1 (0.53) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| Acrylic Acid SCHEMBL1274794 | 0.94 | ALDH1A1 (0.49) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| Benzene SCHEMBL1565370 | 0.94 | MGLL (0.52) | ALDH1A1MGLLTP53CYP3A4 | |
| Formaldehyde SCHEMBL25206470 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| SCHEMBL16307334 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL10494778 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| Ethylene SCHEMBL21354082 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MGLLTP53CYP3A4TSHR | |
| Methane SCHEMBL1504297 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MGLLTP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106542840-A | A kind of Novel fireproof material | 江苏东钢新材料有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-106542840-A | A kind of Novel fireproof material | 江苏东钢新材料有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-105110721-A | Novel light fireproof material and preparation method thereof | SUZHOU KEMIAO NEW MAT CO LTD | 2015-12-02 | — | — | CN | disclosed |