Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842965 | 0.83 | HDAC3 (0.44) | ALDH1A1KMT2APTGS2GRIN2DGRIN3B | |
| SCHEMBL27691961 | 0.81 | TOP2A (0.46) | ALDH1A1KMT2AHSD17B10TSHRP2RX7 | |
| SCHEMBL2582559 | 0.80 | PTGS2 (0.49) | ITGB3ITGAVALDH1A1KMT2APTGS2 | |
| SCHEMBL31139405 | 0.79 | ITGB3 (0.66) | ITGB3ITGAVALDH1A1KMT2AHPGD | |
| SCHEMBL3205146 | 0.79 | ITGB3 (0.66) | ITGB3ITGAVALDH1A1KMT2AHPGD | |
| SCHEMBL9830020 | 0.79 | TOP2A (0.61) | ALDH1A1HSD17B10 | |
| SCHEMBL5470918 | 0.79 | ITGB3 (0.69) | ITGB3ITGAVKMT2AHSD17B10TSHR | |
| SCHEMBL5840221 | 0.79 | MAPT (0.54) | ALDH1A1KMT2ATSHRGRIN2DGRIN3B | |
| Bromide SCHEMBL2582738 | 0.78 | PTGS2 (0.47) | ITGB3ITGAVALDH1A1KMT2APTGS2 | |
| Hydrochloric Acid SCHEMBL10912163 | 0.78 | ITGB3 (0.64) | ITGB3ITGAVALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118086121-A | Burkholderia and application thereof in catalytic chiral resolution | 浙江工业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-115976127-A | Application of Bacillus aryabhattai in preparation of (R) -DMPM | 浙江工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-113667704-A | Method for preparing (R) -N- (2, 6-dimethylphenyl) methyl aminopropionate by two-step enzyme method | 浙江工业大学 | 2021-11-19 | — | — | CN | claimed |
| CN-112195170-A | Immobilized recombinant esterase and application thereof in preparing R-2, 6-dimethylphenyl aminopropionic acid | 浙江工业大学 | 2021-01-08 | — | — | CN | claimed |
| CN-105779409-B | A kind of stereoselectivity esterase, encoding gene, carrier, engineering bacteria and its application | 浙江工业大学 | 2019-11-29 | — | — | CN | claimed |
| CN-118086121-A | Burkholderia and application thereof in catalytic chiral resolution | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-112195170-B | Immobilized recombinant esterase and application thereof in preparing R-2, 6-dimethylphenyl aminopropionic acid | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112195170-B | Immobilized recombinant esterase and application thereof in preparing R-2, 6-dimethylphenyl aminopropionic acid | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-113667704-A | Method for preparing (R) -N- (2, 6-dimethylphenyl) methyl aminopropionate by two-step enzyme method | 浙江工业大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-112195170-A | Immobilized recombinant esterase and application thereof in preparing R-2, 6-dimethylphenyl aminopropionic acid | 浙江工业大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-105779409-A | Stereoselective esterase, coding gene, vector, engineering bacterium and application of stereoselective esterase | 浙江工业大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105779409-A | Stereoselective esterase, coding gene, vector, engineering bacterium and application of stereoselective esterase | 浙江工业大学 | 2016-07-20 | — | — | CN | disclosed |
| CN-105112385-A | Recombinant esterase, coding gene, carrier, engineering bacterium and application | UNIV ZHEJIANG TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |