SCHEMBL28041231

SCHEMBL28041231

C(OCC1CO1)C1CO1.CCCc1ccccc1O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 3/20 0.41
GLA P06280 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
TSHR P16473 2/20 0.38
HRH3 Q9Y5N1 3/20 0.38
HSPA5 P11021 1/20 0.36
MPO P05164 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2123587 0.91 SMN1; SMN2 (0.46) HTR1ASMN1; SMN2ALDH1A1GLATDP1
SCHEMBL17667190 0.89 SMN1; SMN2 (0.37) HTR1ASMN1; SMN2ALDH1A1GLATDP1
SCHEMBL1003516 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL21552431 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL8750967 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL9350609 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL29256323 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL413662 0.89 TDP1 (0.49) HTR1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL27313784 0.88 IAPP (0.46) SMN1; SMN2ALDH1A1TDP1TSHRTP53
SCHEMBL27754020 0.88 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1GLATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105121402-A Novel inclusion compound NIPPON SODA CO 2015-12-02 CN disclosed