SCHEMBL28041236

SCHEMBL28041236

O=CC(=O)C1c2ccccc2CN1c1ccccc1O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.36
HSP90AA1 P07900 9/20 0.35
HSP90AB1 P08238 9/20 0.35
PIN1 Q13526 1/20 0.34
PARP1 P09874 1/20 0.33
TIPARP Q7Z3E1 2/20 0.32
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28281951 0.85 ACE (0.36) ACE
SCHEMBL28002392 0.81 ACE (0.42) ACEHSP90AA1HSP90AB1
Benzene SCHEMBL28150775 0.81 ACE (0.42) ACEHSP90AA1HSP90AB1
SCHEMBL28234415 0.78 ACE (0.36) ACEHSP90AA1HSP90AB1PARP1
SCHEMBL28246850 0.77 HSD17B3 (0.38) ACEHSP90AA1HSP90AB1
SCHEMBL28056681 0.77 SLC6A2 (0.38) ACEHSP90AA1HSP90AB1
SCHEMBL27846951 0.77 SLC6A2 (0.37) ACE
SCHEMBL27920541 0.76 ACE (0.41) ACEHSP90AA1HSP90AB1
SCHEMBL28361507 0.75 ACE (0.40) ACEHSP90AA1HSP90AB1
SCHEMBL27982978 0.75 ACE (0.41) ACEHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104151118-B A kind of alcohol selective oxidation prepares the method for aldehydes or ketones ZHENGZHOU UNIVERSITY (CN) 2015-12-30 CN disclosed
CN-104151118-A Method for preparing aldehyde or ketone by virtue of selective oxidation of alcohol UNIV ZHENGZHOU 2014-11-19 CN disclosed