SCHEMBL28041288

SCHEMBL28041288

CCC(=O)C(Br)=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
FBP1 P09467 2/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
RECQL P46063 1/20 0.44
HTT P42858 1/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
NR1I2 O75469 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
AKR1C1 Q04828 1/20 0.41
LMNA P02545 1/20 0.41
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975332 0.85 CES2 (0.50) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL31352034 0.82 AKR1C3 (0.64) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL12396535 0.82 AKR1C3 (0.64) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL8038875 0.82 MEN1 (0.63) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL30752455 0.78 RECQL (0.55) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL7659594 0.78 MCL1 (0.46) AKR1C3MEN1KMT2AFBP1CES2
SCHEMBL10932008 0.78 AKR1C3 (0.63) AKR1C3MEN1KMT2AFBP1RECQL
SCHEMBL1804115 0.77 AKR1C3 (0.61) AKR1C3MEN1KMT2AFBP1RECQL
SCHEMBL1804114 0.77 AKR1C3 (0.61) AKR1C3MEN1KMT2AFBP1RECQL
SCHEMBL1481710 0.77 AKR1C3 (0.61) AKR1C3MEN1KMT2AFBP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955267-A Alpha-bromo-alpha, beta-unsaturated ketone compound and application thereof in preparation of plant parasitic nematode prevention and control medicines 陕西省生物农业研究所 2024-11-15 CN disclosed
CN-105061504-A Preparation method of P-alkynyl phosphate compound UNIV HUNAN 2015-11-18 CN disclosed