Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028857 | 0.92 | KMT2A (0.56) | MEN1KMT2AAKR1C3CES2CES1 | |
| SCHEMBL8028859 | 0.92 | KMT2A (0.56) | MEN1KMT2AAKR1C3CES2CES1 | |
| SCHEMBL28224152 | 0.88 | MEN1 (0.60) | MEN1KMT2ANR1H4CYP2C9LMNA | |
| SCHEMBL28461515 | 0.86 | MEN1 (0.84) | MEN1KMT2AHTTALDH1A1NR1H4 | |
| SCHEMBL5804949 | 0.85 | CA1 (0.56) | MEN1KMT2AHTTALDH1A1CYP3A4 | |
| SCHEMBL5807201 | 0.85 | CA1 (0.56) | MEN1KMT2AHTTALDH1A1CYP3A4 | |
| SCHEMBL27690788 | 0.83 | KMT2A (0.64) | MEN1KMT2AHTTALDH1A1NR1H4 | |
| SCHEMBL31352034 | 0.83 | AKR1C3 (0.64) | MEN1KMT2AAKR1C3CES2CES1 | |
| SCHEMBL10665879 | 0.83 | MEN1 (0.59) | MEN1KMT2AAKR1C3CES2CES1 | |
| SCHEMBL30752455 | 0.83 | RECQL (0.55) | MEN1KMT2AAKR1C3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | claimed |
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | claimed |
| CN-108358831-B | Polysubstituted carbazole derivative and preparation method thereof | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | disclosed |
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |
| US-4719245-A | TRIMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4703099-A | CATALYTICALLY TRIMERIZING ISOCYANATES | THE DOW CHEMICAL COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| US-4632989-A | KETENE AMINAL-OLEFIN REACTION PRODUCT AS CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| US-4536490-A | REACTION PRODUCT OF KETENE-AMINAL AND UNSATURATED COMPOUND | THE UPJOHN COMPANY (US) | 1985-08-20 | — | — | US | disclosed |