Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.56 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.55 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.55 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245996 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25245494 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25245209 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25245190 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25244738 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25243138 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL25243121 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL23042055 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL23041629 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL23041315 | 0.92 | DGKA (0.87) | DGKANAAAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104987466-A | Polymer absorbent with enhanced polydimethylsiloxane modified cellulose and preparation method thereof | ANHUI CHENGFANG NEW MATERIAL TECHNOLOGY CO LTD | 2015-10-21 | — | — | CN | disclosed |