Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080981 | 0.86 | KDM4E (0.59) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL27590144 | 0.83 | NPC1 (0.50) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL4263725 | 0.82 | MAPT (0.47) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL11576048 | 0.82 | KDM4E (0.51) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL28041606 | 0.81 | KDM4E (0.47) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL29514776 | 0.80 | ESR1 (0.73) | KDM4EMAPTTDP1ESR1ESR2 | |
| SCHEMBL194068 | 0.80 | ESR1 (0.73) | KDM4EMAPTTDP1ESR1ESR2 | |
| SCHEMBL6220647 | 0.80 | DPP4 (0.59) | KDM4EMAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL4436700 | 0.78 | ADORA2A (0.60) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL28823862 | 0.78 | FABP4 (0.54) | KDM4EMAPTMAPK1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086485-B | Prepare the method for poly-substituted quinoline type aromatic ring pyridine derivate | TSINGHUA UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |