Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041367 | 0.89 | KDM4E (0.50) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL27873018 | 0.81 | ESR1 (0.64) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL28041598 | 0.81 | KDM4E (0.56) | KDM4EL3MBTL1ALDH1A1DHFRRAB9A | |
| SCHEMBL9159351 | 0.76 | PSMB5 (0.49) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL27469565 | 0.74 | ACHE (0.70) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL23176987 | 0.74 | MAOA (0.62) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL29249055 | 0.73 | MEN1 (0.52) | KDM4EL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL11576048 | 0.73 | KDM4E (0.51) | KDM4EL3MBTL1ALDH1A1DHFRKMT2A | |
| SCHEMBL4263725 | 0.73 | MAPT (0.47) | KDM4EL3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL11055652 | 0.73 | ACHE (0.67) | KDM4EALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086485-B | Prepare the method for poly-substituted quinoline type aromatic ring pyridine derivate | TSINGHUA UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |