Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289764 | 0.84 | MGAM (0.49) | HDAC8MGAMS1PR3CSNK1DRAB9A | |
| SCHEMBL20490406 | 0.76 | SMN1; SMN2 (0.67) | HDAC8HDAC4HDAC7HDAC5HDAC3 | |
| SCHEMBL2839032 | 0.76 | HDAC4 (1.00) | HDAC8HDAC4HDAC7HDAC5HDAC3 | |
| SCHEMBL29858224 | 0.72 | KDM4E (0.53) | MGAMS1PR3RAB9ANFKB1NFKB2 | |
| SCHEMBL19407337 | 0.72 | KDM4E (0.53) | MGAMS1PR3RAB9ANFKB1NFKB2 | |
| SCHEMBL7831425 | 0.72 | HDAC1 (0.54) | HDAC8HDAC4HDAC7HDAC5HDAC3 | |
| SCHEMBL12915380 | 0.71 | S1PR3 (0.49) | MGAMS1PR3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13898572 | 0.71 | S1PR3 (0.40) | HDAC8HDAC1HDAC2S1PR3GAA | |
| SCHEMBL7831129 | 0.71 | HDAC1 (0.56) | HDAC8HDAC4HDAC7HDAC5HDAC3 | |
| SCHEMBL2840140 | 0.71 | CSNK1D (0.60) | HDAC8HDAC4HDAC7HDAC5HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958475-B | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-25 | — | — | CN | claimed |