Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PRNP | P04156 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041716 | 0.84 | HDAC8 (0.59) | MGAMALDH1A1CNR2S1PR3RAB9A | |
| SCHEMBL7774729 | 0.79 | MGAM (0.52) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL27721065 | 0.77 | MGAM (0.50) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL27519044 | 0.77 | KDM4E (0.51) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL3673078 | 0.77 | KDM4E (0.55) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL1613317 | 0.77 | MGAM (0.50) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL27325063 | 0.77 | MGAM (0.50) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL28818196 | 0.77 | S1PR3 (0.47) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| Anthracene SCHEMBL10416586 | 0.76 | MGAM (0.49) | MGAMKDM4EPRNPRXFP1ALDH1A1 | |
| SCHEMBL12915380 | 0.76 | S1PR3 (0.49) | MGAMKDM4EPRNPRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | claimed |
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |