Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054823 | 1.00 | KEAP1 (0.37) | KEAP1NFE2L2KMT2ATSHRMAPT | |
| SCHEMBL28041541 | 0.84 | KDM4E (0.36) | KEAP1NFE2L2KMT2ATSHRMAPT | |
| SCHEMBL15067314 | 0.83 | POLB (0.41) | KMT2A | |
| SCHEMBL28041534 | 0.83 | MEN1 (0.45) | KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL16054222 | 0.82 | KEAP1 (0.36) | KEAP1NFE2L2KMT2ATSHRMAPT | |
| SCHEMBL28990602 | 0.81 | POLB (0.34) | KEAP1NFE2L2KMT2ATSHRL3MBTL1 | |
| SCHEMBL28041542 | 0.79 | POLB (0.38) | KMT2ATSHRLMNAALDH1A1HPGD | |
| SCHEMBL27992292 | 0.75 | TRPA1 (0.37) | KMT2ATSHRLMNAGAAALDH1A1 | |
| SCHEMBL28041589 | 0.74 | ABCB1 (0.37) | KMT2ATSHRMAPTL3MBTL1LMNA | |
| SCHEMBL27992397 | 0.73 | POLB (0.39) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136416-B | Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound | 比皮艾思药物研发有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |