⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13741513 | 0.77 | — | — | |
| SCHEMBL4272432 | 0.76 | — | — | |
| SCHEMBL726269 | 0.75 | — | — | |
| SCHEMBL4325166 | 0.74 | — | — | |
| SCHEMBL2066130 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL14507897 | 0.67 | — | — | |
| SCHEMBL20304614 | 0.65 | — | — | |
| SCHEMBL799360 | 0.65 | — | — | |
| SCHEMBL798845 | 0.65 | — | — | |
| SCHEMBL8629366 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781258-B | Hydroxy-substituted imidazo [1,2-a ] pyridinecarboxamides and their use as soluble guanylate cyclase stimulators | 拜耳制药股份公司 | 2017-09-22 | — | — | CN | disclosed |
| CN-106715426-A | Cyano-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳医药股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104981470-B | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳制药股份公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |