Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 12/20 | 0.42 |
| ▸ | FEN1 | P39748 | 12/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046629 | 0.81 | HTR1A (0.50) | ALOX5APFEN1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL16055536 | 0.78 | CA1 (0.44) | ALOX5APFEN1 | |
| SCHEMBL12994249 | 0.74 | HTR2C (0.41) | ALOX5APFEN1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL15912627 | 0.74 | ALOX5AP (0.51) | ALOX5APFEN1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL15226931 | 0.74 | SLC6A2 (0.51) | ALOX5APFEN1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL1994314 | 0.74 | MEP1B (0.41) | MEP1B | |
| SCHEMBL25981341 | 0.73 | HTR2C (0.51) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27718189 | 0.73 | ALOX5AP (0.36) | ALOX5APFEN1GRM2 | |
| SCHEMBL27718187 | 0.73 | ALOX5AP (0.36) | ALOX5APFEN1GRM2 | |
| SCHEMBL26854255 | 0.73 | ALOX5AP (0.46) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715426-A | Cyano-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳医药股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104981470-B | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳制药股份公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |