Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464853 | 0.82 | TDP1 (0.38) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16553237 | 0.78 | TDP1 (0.42) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL27658984 | 0.78 | TDP1 (0.42) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28041980 | 0.76 | — | — | |
| SCHEMBL303194 | 0.74 | TDP1 (0.39) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| Aniline SCHEMBL28065762 | 0.74 | TSHR (0.35) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL28025398 | 0.74 | — | — | |
| SCHEMBL27763136 | 0.72 | TDP1 (0.42) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28029353 | 0.71 | TDP1 (0.35) | TDP1GAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL692446 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TSHRHSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121544-A | Curable composition, and joint structure produced using same | SEKISUI FULLER CO LTD | 2015-12-02 | — | — | CN | disclosed |