SCHEMBL303194

SCHEMBL303194

CCC[Si](OCC)(OCC)OC(C)Nc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.39
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 3/20 0.35
ALOX15 P16050 3/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX12 P18054 2/20 0.35
THRB P10828 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35
ATM Q13315 1/20 0.35
GAA P10253 2/20 0.35
HIF1A Q16665 2/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
KDM4E B2RXH2 2/20 0.33
KCNH3 Q9ULD8 2/20 0.32
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27763136 0.80 TDP1 (0.42) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL27658984 0.80 TDP1 (0.42) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL16553237 0.80 TDP1 (0.42) TDP1ALDH1A1CYP3A4ALOX15TSHR
Diphenylamine SCHEMBL28715243 0.77 HSD17B10 (0.44) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL27889090 0.76 ADORA3 (0.35) ALDH1A1CYP3A4LMNA
SCHEMBL31028386 0.75 SIGMAR1 (0.40) ALDH1A1CYP3A4TSHR
SCHEMBL1261812 0.75 ALDH1A1 (0.42) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL8464853 0.75 TDP1 (0.38) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL28041978 0.74 TDP1 (0.35) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL27245488 0.74 ALDH1A1 (0.45) TDP1ALDH1A1CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037452-A1 ONE-PART CURABLE RESIN COMPOSITION Adeka Corporation (JP) 2016-06-29 EP disclosed
US-8092359-B1 Fuser member and fuser member surface layer EASTMAN KODAK COMPANY (US) 2012-01-10 US disclosed
EP-1443368-A2 Layer comprising nonfibriliatable and autoadhesive plastic particles, and method of preparation Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2004-08-04 EP disclosed