SCHEMBL28042007

SCHEMBL28042007

Cc1ccc(S(=O)(=O)N(C(N)=O)c2ccccc2OS(=O)(=O)c2cccc(C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.43
TP53 P04637 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
GAA P10253 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
POLB P06746 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 5/20 0.40
MAPK1 P28482 1/20 0.40
HTR6 P50406 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28042006 0.81 TP53 (0.56) TP53GAAMAPTALDH1A1POLB
SCHEMBL28082162 0.81 C5AR1 (0.46) C5AR1TP53MEN1KMT2AGAA
SCHEMBL6465059 0.76 C5AR1 (0.54) C5AR1TP53MEN1KMT2AMAPT
SCHEMBL6326490 0.75 C5AR1 (0.53) C5AR1TP53MEN1KMT2AGAA
SCHEMBL6243114 0.75 C5AR1 (0.53) C5AR1TP53MEN1KMT2AMAPT
SCHEMBL27895491 0.74 PPARG (0.48) TP53MEN1KMT2AGAAMAPT
SCHEMBL21753696 0.74 PPARG (0.48) TP53MEN1KMT2AGAAMAPT
SCHEMBL6324948 0.74 LMNA (0.63) C5AR1TP53MEN1KMT2AMAPT
SCHEMBL28082161 0.74 TP53 (0.53) TP53MEN1KMT2AGAAMAPT
SCHEMBL6243974 0.73 C5AR1 (0.50) C5AR1TP53MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105082815-A Thermosensitive recording material and preparation method thereof GUANGDONG GUANHAO HIGH TECH CO LTD 2015-11-25 CN claimed
CN-105082815-A Thermosensitive recording material and preparation method thereof GUANGDONG GUANHAO HIGH TECH CO LTD 2015-11-25 CN disclosed