SCHEMBL28042233

SCHEMBL28042233

CC1=CCC(COC=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HPGD P15428 1/20 0.37
LMNA P02545 3/20 0.36
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNA7 P36544 1/20 0.33
STAT3 P40763 1/20 0.33
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13134778 0.80 NPC1 (0.50) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL29163572 0.79 SCN9A (0.33) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL21449552 0.78 NPC1 (0.49) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL29163587 0.77 DRD3 (0.41)
SCHEMBL5086010 0.73 ALDH1A1 (0.59) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL2563770 0.73 LMNA (0.45) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL20349204 0.72 NPC1 (0.58) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL14527870 0.71 ALDH1A1 (0.50) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL14527869 0.71 ALDH1A1 (0.50) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2
SCHEMBL10777628 0.71 ALDH1A1 (0.50) NPC1ALDH1A1TSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017010-B Preparation method of terephthalic acid and preparation method of 4-methyl-3-cyclohexene-1-methyl formate 远东新世纪股份有限公司 2016-08-17 CN claimed
CN-105017010-B Preparation method of terephthalic acid and preparation method of 4-methyl-3-cyclohexene-1-methyl formate 远东新世纪股份有限公司 2016-08-17 CN disclosed
CN-105017010-B Preparation method of terephthalic acid and preparation method of 4-methyl-3-cyclohexene-1-methyl formate 远东新世纪股份有限公司 2016-08-17 CN disclosed
CN-105017010-A Preparation method of terephthalic acid and preparation method of 4-methyl-3-cyclohexene-1-methyl formate FAR EASTERN NEW CENTURY CORP 2015-11-04 CN disclosed