SCHEMBL28042255

SCHEMBL28042255

Cc1cc(C(=O)O)cc(C(=O)O)c1.Nc1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.53
KEAP1 Q14145 1/20 0.53
TPMT P51580 1/20 0.48
HCAR1 Q9BXC0 1/20 0.47
CYP2C9 P11712 1/20 0.44
ATIC P31939 1/20 0.44
CYP2C19 P33261 1/20 0.44
CDC25B P30305 4/20 0.43
CDC25A P30304 1/20 0.43
CDC25C P30307 1/20 0.43
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL27522273 0.87 HSD17B10 (0.61) HSD17B10ALDH1A1CYP3A4HPGDTSHR
SCHEMBL8000087 0.84 ALDH1A1 (0.57) HSD17B10ALDH1A1CYP3A4HPGDTSHR
Benzoic Acid SCHEMBL27454196 0.83 TSHR (0.65) HSD17B10ALDH1A1CYP3A4HPGDTSHR
Naphthoic Acid SCHEMBL27788340 0.83 NR4A1 (0.68) HSD17B10ALDH1A1CYP3A4HPGDTPMT
SCHEMBL27982178 0.82 NR4A1 (0.53) ALDH1A1CYP3A4TPMTHCAR1CYP2C9
Naphthalene SCHEMBL27937962 0.81 TPMT (0.61) ALDH1A1TSHRTPMTHCAR1NR4A1
Naphthalene SCHEMBL27658466 0.81 TPMT (0.67) ALDH1A1TSHRTPMTHCAR1NR4A1
SCHEMBL27786322 0.80 HSD17B10 (0.50) HSD17B10ALDH1A1CYP3A4HPGDTSHR
Acetic Acid SCHEMBL28299908 0.79 ALDH1A1 (0.71) HSD17B10ALDH1A1CYP3A4HPGDTSHR
Acetic Acid SCHEMBL27357071 0.79 ALDH1A1 (0.71) HSD17B10ALDH1A1CYP3A4HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105136787-A Detection reagent for mono-hydroxyphenyl metabolin urine SHANGHAI FEI JI BIOTECHNOLOGY CO LTD 2015-12-09 CN disclosed