SCHEMBL8000087

SCHEMBL8000087

Nc1cc(N)cc(C(=O)O)c1.Nc1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
HSD17B10 Q99714 4/20 0.57
HPGD P15428 4/20 0.57
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
KEAP1 Q14145 1/20 0.57
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
ATIC P31939 1/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
CDC25B P30305 5/20 0.46
CDC25A P30304 1/20 0.46
CDC25C P30307 1/20 0.46
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
PLAU P00749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Aminobenzoic Acid SCHEMBL8003488 0.89 HSD17B10 (0.55) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Isophthalic Acid SCHEMBL27522273 0.86 HSD17B10 (0.61) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Benzoic Acid SCHEMBL27454196 0.86 TSHR (0.65) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Aminobenzoic Acid SCHEMBL8000166 0.85 TSHR (0.59) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL28042255 0.84 HSD17B10 (0.53) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL8003001 0.82 CDC25B (0.48) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Oxalic Acid SCHEMBL4292229 0.80 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Carbamic Acid SCHEMBL6583530 0.80 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL343609 0.79 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDCYP3A4TSHR
Acetic Acid SCHEMBL28299908 0.78 ALDH1A1 (0.71) ALDH1A1HSD17B10HPGDCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117996-A COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS NOVO NORDISK A/S (DK) 2000-09-12 US disclosed