Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505749 | 0.81 | NT5E (0.44) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL7898997 | 0.79 | NSD2 (0.42) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL28545556 | 0.78 | ALDH1A1 (0.39) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL1717787 | 0.78 | ALDH1A1 (0.48) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL28111354 | 0.75 | NSD2 (0.43) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL10351830 | 0.74 | NSD2 (0.53) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL2684700 | 0.73 | TTR (0.53) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL28334959 | 0.72 | GAA (0.47) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL3029818 | 0.71 | TTR (0.51) | CASP6GAANSD2PLCG1DNMT1 | |
| SCHEMBL8421128 | 0.71 | ALDH1A1 (0.57) | CASP6GAANSD2PLCG1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143260-A | Antibodies specific for a novel epitope on CEMX of human membrane bound IgE and their use for treating IgE-mediated diseases | ACADEMIA SINICA | 2015-12-09 | — | — | CN | disclosed |