Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083021 | 0.85 | NSD2 (0.44) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL28042421 | 0.84 | L3MBTL1 (0.46) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL1717789 | 0.84 | ALDH1A1 (0.44) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL124315 | 0.84 | ALDH1A1 (0.46) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL7441311 | 0.81 | GPR35 (0.47) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL27464031 | 0.81 | GPR35 (0.44) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL195393 | 0.81 | GPR35 (0.44) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL26980 | 0.81 | GPR35 (0.44) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL1717787 | 0.79 | ALDH1A1 (0.48) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL19945968 | 0.79 | GPR35 (0.43) | NSD2GAAPLCG1DNMT1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265220-B1 | NON-IMMUNOCHEMICAL METHOD BY REACTING A COMPOUND COMPRISING CIS-1,4-DIOXO-2-BUTENE MOIETY OR HYDROLYTICALLY DERIVED PRECURSOR WITH HOMOCYSTEINE, THEN DETECTING PRODUCT WITHOUT SEPARATION FROM LIQUID | ULLMAN EDWIN F (US) | 2001-07-24 | — | — | US | disclosed |
| WO-2000000821-A1 | ASSAY FOR HOMOCYSTEINE | ULLMAN EDWIN F (US) | 2000-01-06 | — | — | WO | disclosed |