Fluoride

Fluoride

SCHEMBL28042437

CCOc1ccccc1S(N)(=O)=O.F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.58
CA2 P00918 8/20 0.58
CA9 Q16790 6/20 0.58
CA12 O43570 5/20 0.58
CA14 Q9ULX7 2/20 0.58
PTGES2 Q9H7Z7 1/20 0.53
ALDH1A1 P00352 3/20 0.50
CA7 P43166 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GLA P06280 1/20 0.44
CA4 P22748 3/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CYP2C9 P11712 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
HTR1A P08908 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5579618 0.98 CA1 (0.60) CA1CA2CA9CA12CA14
SCHEMBL29469832 0.98 CA1 (0.60) CA1CA2CA9CA12CA14
SCHEMBL27518574 0.84 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL29469878 0.84 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL1649916 0.84 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL10749628 0.83 PTGES2 (0.46) CA1CA2CA9CA12CA14
SCHEMBL7108847 0.82 ALDH1A1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL1334805 0.82 CYP2C9 (0.56) CA1CA2CA9CA12CA14
SCHEMBL28115347 0.82 CA12 (0.54) CA1CA2CA9CA12CA14
SCHEMBL31411936 0.82 CA1 (0.54) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017098-A Preparation technology of alkyloxybenzsulfamide and its derivatives DALIAN QIKAI MEDICAL TECHNOLOGY CO LTD 2015-11-04 CN disclosed