SCHEMBL5579618

SCHEMBL5579618

CCOc1ccccc1S(N)(=O)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.60
CA2 P00918 8/20 0.60
CA9 Q16790 6/20 0.60
CA12 O43570 5/20 0.60
CA14 Q9ULX7 2/20 0.60
PTGES2 Q9H7Z7 1/20 0.55
ALDH1A1 P00352 3/20 0.52
CA7 P43166 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GLA P06280 1/20 0.46
CA4 P22748 3/20 0.45
CA6 P23280 2/20 0.45
CA5A P35218 2/20 0.45
CYP2C9 P11712 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
HTR1A P08908 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469832 1.00 CA1 (0.60) CA1CA2CA9CA12CA14
Fluoride SCHEMBL28042437 0.98 CA1 (0.58) CA1CA2CA9CA12CA14
SCHEMBL27518574 0.86 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL29469878 0.85 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL1649916 0.85 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL10749628 0.84 PTGES2 (0.46) CA1CA2CA9CA12CA14
SCHEMBL7108847 0.84 ALDH1A1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL1334805 0.84 CYP2C9 (0.56) CA1CA2CA9CA12CA14
SCHEMBL31411936 0.84 CA1 (0.54) CA1CA2CA9CA12CA14
SCHEMBL28115347 0.84 CA12 (0.54) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642791-A Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide 南开大学 2020-01-03 CN claimed
WO-2026099404-A1 SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER QUBIT PHARMACEUTICALS (FR) 2026-05-15 WO disclosed
EP-4741375-A1 SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER Qubit Pharmaceuticals (FR) 2026-05-13 EP disclosed
EP-4229045-B1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BROAD INST INC (US) 2025-11-12 EP disclosed
US-12357603-B2 Acyl sulfonamides for treating cancer BAYER AKTIENGESELLSCHAFT (DE) 2025-07-15 US disclosed
EP-4472682-A1 SENSORS FOR ANTIMICROBIAL BIPHASIC POLYMERS, AND SYSTEMS AND METHODS INCORPORATING THE SAME HRL Laboratories, LLC (US) 2024-12-11 EP disclosed
US-20240287048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-08-29 US disclosed
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-08-22 US disclosed
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-18 US disclosed
US-11760722-B2 Inhibitors of cysteine proteases and methods of use thereof ASCLETIS BIOSCIENCE CO., LTD. (CN) 2023-09-19 US disclosed
CN-1240429-A Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors AMERICAN CYANAMID CO (US) 2000-01-05 CN disclosed
US-5990353-A DEMETALLIZING AN ARYLSULFONAMIDE ALKALI METAL SALT WITH AN AROMATIC ISOCYANATE COMPOUND IN AT LEAST ONE SOLVENT; USE AS A COLOR DEVELOPER FOR A THERMAL RECORDING MATERIAL WITH IMPROVED OIL RESISTANCE AND NONPLASTICIZED YAMAMOTO CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0879816-A1 Process for producing arylsulfonylureide compounds Yamamoto Chemicals, Inc. (JP) 1998-11-25 EP disclosed
EP-0694041-A1 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING N-ALPHA-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-31 EP disclosed
EP-0327318-B1 Heat-sensitive recording materials FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
US-4975353-A Support and layer of diazo compound, coupling component for coloration and basic compound FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed
US-4895826-A STORAGE STABILITY; DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1990-01-23 US disclosed
EP-0327318-A2 Heat-sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0323887-A2 Heat-sensitive diazo recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-12 EP disclosed
EP-0288240-A2 Heat-sensitive diazo recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA1 2072/4885CA2 2985/4885CA9 2304/4885
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 CA1 4424/4885CA2 2718/4885CA9 4465/4885
US-12357603-B2 Acyl sulfonamides for treating cancer KAT6A, KAT6B, KAT2A CA1 1716/4885CA2 2884/4885CA9 2045/4885
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA1 1714/4885CA2 2865/4885CA9 1575/4885
US-11760722-B2 Inhibitors of cysteine proteases and methods of use thereof SERPINB1, PREP, DNPEP CA1 197/4885CA2 661/4885CA9 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.