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Coenzyme_A

Coenzyme_A

SCHEMBL28042496

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCS.NCCCC(=O)O

nearest known ligand 0.90

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 3/20 0.90
▸ AURKA O14965 2/20 0.90
▸ CHAT P28329 2/20 0.90
▸ NAA50 Q9GZZ1 2/20 0.90
▸ KAT5 Q92993 2/20 0.90
▸ KAT2B Q92831 1/20 0.90
▸ CREBBP Q92793 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coenzyme_A SCHEMBL61157 1.00 EP300 (0.90) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL25285622 0.97 EP300 (0.92) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL28724953 0.96 EP300 (0.90) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL2119660 0.96 EP300 (0.90) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL15969462 0.95 EP300 (0.89) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL2486324 0.95 EP300 (0.89) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18180012 0.95 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682057 0.95 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL13500623 0.95 EP300 (1.00) EP300AURKACHATNAA50KAT5
Coenzyme_A SCHEMBL18682056 0.95 EP300 (1.00) EP300AURKACHATNAA50KAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107384846-A Produce microorganism and the correlation technique of 1,4 butanediols 基因组股份公司 2017-11-24 — — CN disclosed
CN-102762735-B Microorganisms producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-hydroxybutyryl-COA, putrescine and related compounds and related methods 基因组股份公司 2016-08-03 — — CN disclosed
CN-105441374-A Microorganism for producing 1, 4-butanediol, 4-hydroxybutyraldehyde, 4-maloyl-COA, putrescine and related compound and related method thereof GENOMATICA INC 2016-03-30 — — CN disclosed