Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.90 |
| ▸ | AURKA | O14965 | 2/20 | 0.90 |
| ▸ | CHAT | P28329 | 2/20 | 0.90 |
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.90 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.90 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.90 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coenzyme_A SCHEMBL28042496 | 1.00 | EP300 (0.90) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL25285622 | 0.97 | EP300 (0.92) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL2119660 | 0.96 | EP300 (0.90) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL28724953 | 0.96 | EP300 (0.90) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL2486324 | 0.95 | EP300 (0.89) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL15969462 | 0.95 | EP300 (0.89) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL26752 | 0.95 | EP300 (1.00) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL18033983 | 0.95 | EP300 (1.00) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL18675521 | 0.95 | EP300 (1.00) | EP300AURKACHATNAA50KAT5 | |
| Coenzyme_A SCHEMBL26753 | 0.95 | EP300 (1.00) | EP300AURKACHATNAA50KAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056706-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | Genomatica, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| EP-3392340-B1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA INC (US) | 2022-01-05 | — | — | EP | disclosed |
| US-20190264240-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | GENOMATICA INC (US) | 2019-08-29 | — | — | US | disclosed |
| EP-3392340-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | Genomatica, Inc. (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20180142269-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA INC (US) | 2018-05-24 | — | — | US | disclosed |
| EP-2438178-B1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-20160376614-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | GENOMATICA INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-9434964-B2 | Microorganisms for the production of 1,4-butanediol and related methods | GENOMATICA, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9175297-B2 | Microorganisms for the production of 1,4-Butanediol | GENOMATICA, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130109069-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2013-05-02 | — | — | US | disclosed |
| US-20120225463-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-8129169-B2 | Microorganisms for the production of 1,4-butanediol and related methods | GENOMATICA, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110045575-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. | 2011-02-24 | — | — | US | disclosed |
| US-7858350-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100112654-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2010-05-06 | — | — | US | disclosed |