SCHEMBL28042519

SCHEMBL28042519

Cc1cc(C)cc(-n2ccc(-c3ccccc3C(N)=O)n2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.43
TYK2 P29597 1/20 0.43
MAP4K2 Q12851 1/20 0.40
HTT P42858 1/20 0.39
TGFBR1 P36897 4/20 0.39
RCE1 Q9Y256 1/20 0.38
SCN9A Q15858 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PARP1 P09874 2/20 0.36
PARP2 Q9UGN5 1/20 0.36
PARP3 Q9Y6F1 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CCNA1 P78396 1/20 0.36
CSNK1A1 P48729 1/20 0.36
TYRO3 Q06418 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
GRM5 P41594 1/20 0.36
KAT6A Q92794 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626876 0.80 BCAT2 (0.44) BCAT2TYK2MAP4K2TGFBR1PARP1
SCHEMBL1380693 0.77 BCAT2 (0.53) BCAT2TGFBR1SCN9AKMT2APARP1
SCHEMBL30964842 0.77 BCAT2 (0.53) BCAT2TGFBR1SCN9AKMT2APARP1
SCHEMBL27279237 0.75 BCAT2 (0.63) BCAT2PARP1CSNK1A1TYRO3DYRK1B
SCHEMBL28042524 0.75 PARP1 (0.54) BCAT2TYK2TGFBR1SCN9AKMT2A
SCHEMBL31105398 0.75 BCAT2 (0.50) BCAT2MAP4K2TGFBR1PARP1CSNK1A1
SCHEMBL28042578 0.72 NPC1 (0.41) BCAT2HTTTGFBR1MEN1KMT2A
SCHEMBL16654017 0.72 KDM4C (0.51) BCAT2MAP4K2KMT2APARP1CSNK1A1
SCHEMBL28522305 0.67 MYC (0.56) BCAT2HTTPARP1CSNK1A1TYRO3
SCHEMBL3529606 0.67 BCAT2 (0.51) BCAT2TGFBR1KMT2APARP1CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 CN disclosed