Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042524 | 0.84 | PARP1 (0.54) | BCAT2TGFBR1CAPN1TYK2JAK2 | |
| SCHEMBL28042578 | 0.81 | NPC1 (0.41) | BCAT2TGFBR1CAPN1ALDH1A1KDM4E | |
| SCHEMBL28042519 | 0.80 | BCAT2 (0.43) | BCAT2MAP4K2TGFBR1TYK2PARP1 | |
| SCHEMBL1380693 | 0.78 | BCAT2 (0.53) | BCAT2TGFBR1ALDH1A1KDM4EMAPT | |
| SCHEMBL30964842 | 0.78 | BCAT2 (0.53) | BCAT2TGFBR1ALDH1A1KDM4EMAPT | |
| SCHEMBL21141881 | 0.71 | KMT2A (0.53) | CAPN1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL1788703 | 0.70 | BCAT2 (0.59) | BCAT2MYCALDH1A1KDM4EMAPT | |
| SCHEMBL28042579 | 0.70 | PARP1 (0.40) | CAPN1ALDH1A1KDM4EPARP1 | |
| SCHEMBL16654017 | 0.70 | KDM4C (0.51) | BCAT2MAP4K2JAK2MAPTPARP1 | |
| SCHEMBL15964204 | 0.70 | ALDH1A1 (0.62) | MAPK14ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548854-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-01-10 | — | — | US | disclosed |
| US-11332448-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548854-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | BCAT2 2298/4885MAP4K2 3394/4885TGFBR1 4498/4885 |
| US-11332448-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | BCAT2 2298/4885MAP4K2 3394/4885TGFBR1 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.