Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15052830 | 0.90 | FAP (0.35) | FAPIDO1 | |
| SCHEMBL17459885 | 0.90 | FAP (0.36) | FAPLPAR3LPAR1ENPP2SMN1; SMN2 | |
| SCHEMBL18309147 | 0.80 | FAP (0.35) | FAPIDO1 | |
| SCHEMBL16343575 | 0.79 | SCN5A (0.33) | — | |
| SCHEMBL7643791 | 0.79 | FAP (0.36) | FAPIDO1 | |
| SCHEMBL17034310 | 0.78 | FAP (0.36) | FAPIDO1 | |
| SCHEMBL21248328 | 0.77 | FAP (0.37) | FAPIDO1 | |
| SCHEMBL25019683 | 0.77 | FAP (0.34) | FAPIDO1 | |
| SCHEMBL5615689 | 0.76 | FAP (0.37) | FAPIDO1 | |
| SCHEMBL17883369 | 0.76 | FAP (0.35) | FAPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515603-A | Bicyclic and monocyclic nucleoside analogs for the treatment of hepatitis E | 杨森制药公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-105073766-A | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA INC (US) | 2015-11-18 | — | — | CN | disclosed |