SCHEMBL25019683

SCHEMBL25019683

CCOP(=O)(O)OCOC(=O)OC(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAP Q12884 2/20 0.34
PPARD Q03181 1/20 0.32
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
IDO1 P14902 2/20 0.31
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643791 0.93 FAP (0.36) FAPTSHRIDO1
SCHEMBL15052830 0.87 FAP (0.35) FAPIDO1
SCHEMBL3750750 0.85 ALDH1A1 (0.44) PPARDTSHRALDH1A1LMNA
SCHEMBL25657140 0.85 FAP (0.33) FAPTSHR
SCHEMBL30514365 0.84 PLA2G2A (0.36) FAPTSHR
SCHEMBL17518047 0.84 TSHR (0.46) FAPPPARDTSHRALDH1A1IDO1
SCHEMBL17034307 0.83 FAP (0.34) FAPTSHRALDH1A1IDO1LMNA
SCHEMBL18309147 0.82 FAP (0.35) FAPPPARDTSHRIDO1LMNA
SCHEMBL17228538 0.82 P2RY10 (0.38) FAP
SCHEMBL17459885 0.82 FAP (0.36) FAPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134134-A1 STING AGONISTIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2023-02-15 EP disclosed