Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376226 | 0.79 | LMNA (0.63) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL29901650 | 0.78 | CA12 (0.73) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL1648027 | 0.78 | CA12 (0.73) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17169392 | 0.77 | LMNA (0.86) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL29155366 | 0.76 | CA12 (0.70) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL1648120 | 0.76 | VKORC1 (0.70) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17022461 | 0.76 | LMNA (0.70) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17022685 | 0.75 | LMNA (0.68) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17022677 | 0.75 | LMNA (0.68) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL10613511 | 0.75 | CA12 (0.69) | ALDH1A1KDM4EMAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111176-A | 3-phenoxyacetyl-4-hydroxycoumarin derivative, synthetic method and application | UNIV NANKAI | 2015-12-02 | — | — | CN | disclosed |
| CN-105111176-A | 3-phenoxyacetyl-4-hydroxycoumarin derivative, synthetic method and application | UNIV NANKAI | 2015-12-02 | — | — | CN | disclosed |