Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169392 | 0.84 | LMNA (0.86) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL3527681 | 0.83 | CA12 (1.00) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL30933370 | 0.83 | CA12 (1.00) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL11376226 | 0.79 | LMNA (0.63) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL2761745 | 0.79 | ALDH1A1 (0.72) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL17169389 | 0.79 | CA12 (0.69) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL7949780 | 0.78 | LMNA (0.64) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL29901650 | 0.78 | CA12 (0.73) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL1648027 | 0.78 | CA12 (0.73) | CA12CA9LMNAHTTALDH1A1 | |
| SCHEMBL17022691 | 0.77 | LMNA (0.56) | CA12CA9LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141185-A | Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2022-10-04 | — | — | CN | claimed |
| CN-115141185-B | Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-115141185-B | Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-115141185-A | Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-115141185-A | Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2022-10-04 | — | — | CN | disclosed |