Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603443 | 0.86 | CYP3A4 (0.35) | TSHRCYP3A4TP53ALDH1A1MAPK1 | |
| SCHEMBL12878756 | 0.73 | NPC1 (0.33) | CYP3A4ALDH1A1 | |
| SCHEMBL21552685 | 0.73 | AOC3 (0.37) | — | |
| SCHEMBL4498724 | 0.73 | AOC3 (0.37) | ALDH1A1 | |
| SCHEMBL19122860 | 0.73 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL29661608 | 0.73 | AOC3 (0.37) | ALDH1A1 | |
| SCHEMBL505928 | 0.73 | — | — | |
| SCHEMBL4492757 | 0.73 | CYP3A4 (0.34) | TSHRCYP3A4TP53ALDH1A1ALOX15 | |
| SCHEMBL174080 | 0.70 | TXNRD1 (0.37) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL30474091 | 0.70 | MEN1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275072-B | The preparation method of saracatinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |