Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507057 | 0.80 | TTBK1 (0.47) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL2505047 | 0.80 | TTBK1 (0.50) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL28230659 | 0.76 | ALDH1A1 (0.45) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL2502095 | 0.76 | TTBK1 (0.43) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL19867355 | 0.76 | POLB (0.45) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL12403903 | 0.76 | TTBK1 (0.43) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL9258744 | 0.76 | KDM4E (0.45) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL4025660 | 0.74 | POLB (0.57) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL18893494 | 0.73 | TTBK1 (0.45) | TTBK1TTBK2POLBMAPK1ABCG2 | |
| SCHEMBL6927430 | 0.73 | ALDH1A1 (0.49) | TTBK1TTBK2POLBMAPK1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275072-B | The preparation method of saracatinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |