Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507057 | 0.76 | TTBK1 (0.47) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL28042597 | 0.76 | TTBK1 (0.47) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL2505047 | 0.76 | TTBK1 (0.50) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL28230659 | 0.75 | ALDH1A1 (0.45) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL4025660 | 0.74 | POLB (0.57) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL6823246 | 0.72 | KDM4E (0.56) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL6316842 | 0.72 | LMNA (0.56) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL16084001 | 0.72 | ABCG2 (0.44) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL2502095 | 0.71 | TTBK1 (0.43) | POLBALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL9258744 | 0.71 | KDM4E (0.45) | POLBALDH1A1MAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931280-B1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | PHUSIS THERAPEUTICS INC (US) | 2018-02-14 | — | — | EP | disclosed |