Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997312 | 0.77 | KDM4E (0.39) | ADRA2CCYP2D6MEN1KMT2APMP22 | |
| SCHEMBL30933030 | 0.76 | PPM1B (0.45) | TSHRALOX15CYP2C19 | |
| SCHEMBL6551846 | 0.76 | PPM1B (0.45) | TSHRALOX15CYP2C19 | |
| SCHEMBL14874330 | 0.73 | PPM1B (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14874331 | 0.73 | PPM1B (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16448666 | 0.72 | PPM1B (0.45) | TSHRALOX15CYP2C19 | |
| SCHEMBL7354850 | 0.72 | PPM1B (0.45) | TSHRALOX15CYP2C19 | |
| SCHEMBL30849529 | 0.72 | CHRM2 (0.47) | CYP2D6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL417319 | 0.72 | CHRM2 (0.47) | CYP2D6MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL3000349 | 0.72 | CHRM2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402989-B | Tetrazole compound and preparation and application thereof | ZAFGEN CORP. (US) | 2016-04-06 | — | — | CN | disclosed |