Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.74 |
| ▸ | MMP3 | P08254 | 10/20 | 0.74 |
| ▸ | MMP13 | P45452 | 10/20 | 0.74 |
| ▸ | MMP9 | P14780 | 10/20 | 0.74 |
| ▸ | MMP1 | P03956 | 9/20 | 0.74 |
| ▸ | MMP7 | P09237 | 9/20 | 0.74 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.68 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.68 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.68 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004878 | 1.00 | MMP2 (0.74) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL6797666 | 0.89 | MMP2 (0.91) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL2161562 | 0.89 | MMP2 (0.91) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL3842066 | 0.89 | MMP2 (0.91) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL21538657 | 0.86 | MMP9 (0.73) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL6296214 | 0.86 | MMP9 (0.73) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL6302637 | 0.86 | MMP9 (0.73) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7406967 | 0.85 | MMP2 (1.00) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL7406959 | 0.85 | MMP2 (1.00) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL12467075 | 0.84 | MMP2 (0.56) | MMP2MMP3MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-B | Novel sulfonamide TRPA1 receptor antagonists | 阿里奥制药有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |